Testing Services

Title: Standard Test Method for Testing Disinfectant Efficacy against Pseudomonas aeruginosa Biofilm using the MBEC Assay

Scope:   Specifies the operational parameters required to grow and treat a Pseudomonas aeruginosa biofilm in a high throughput screening assay known as the MBEC (Minimum Biofilm Eradication Concentration) Assay. Biofilm is established on polystyrene pegs (on the lid of a 96-well plate) under batch conditions (that is, no flow of nutrients into or out of an individual well) with gentle mixing. The established biofilm is transferred to a new receiver plate for disinfectant efficacy testing. Defines the specific operational

NOTE:  Nick Allan and Merle Olson wrote this method for ASTM.

Title:    Test Method for Antifungal Activity, Assessment on Textile Materials: Mildew and Rot Resistance of Textile Materials

Scope:   To determine the susceptibility of textile materials to mildew and rot and to evaluate the efficacy of fungicides on textile materials. 

Title:  Standard Practice to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces

Scope:   Used to evaluate the virucidal efficacy of liquid, aerosol, or trigger-spray microbicides intended for use on inanimate, nonporous environmental surfaces. May be employed with most viruses, which can be grown in cultured cells. 

Title:  Test Method for Assessment of Antibacterial Finishes on Textile Materials

Scope:   Quantitative procedure for the evaluation of the degree of antibacterial activity of coatings/treatments/finishes on textiles. 

Title:  Standard Practices for Evaluation of Inactivators of Antimicrobial Agents

Scope:  Used to determine the effectiveness of methodologies, procedures, and materials intended for inactivating (neutralizing, quenching) the microbicidal properties of antimicrobial agents; to ensure that no components of the neutralizing  procedures and materials, themselves, exert an inhibitory effect on microorganisms targeted for recovery; and to demonstrate that the antimicrobial chemistry tested is microbicidal.

Title:  Standard Quantitative Carrier Test Method to Evaluate the Bactericidal, Fungicidal, Mycobactericidal, and Sporicidal Potencies of Liquid Chemicals .

Scope:  Method is fully quantitative and it also avoids any loss of viable organisms through wash off, making it possible to produce statistically valid data using many fewer test and control carriers than other quantitative methods based on most probable numbers (MPN). The design of the carriers makes it possible to place into each a precisely measured volume of the test suspension. Can be performed with or without a soil load to determine the effect of such loading on microbicide performance.

Title:  Antimicrobial Efficacy Testing

Scope:  Describes procedures to demonstrate the effectiveness of antimicrobial preservatives, with acceptance criteria that apply to a product in the original, sealed container in which it is distributed by the manufacturer.

Title:  Dissolution 

Scope:  Describes procedures to quantify the release of an API from a pharmaceutical product.

Title:  Drug Release  

Scope: This test is provided to determine compliance with drug release or dissolution requirements where stated in the individual monographs for transdermal systems (TDS) and other dosage forms.

Title:  Ultraviolet-Visible Spectroscopy   

Scope:  Describes how to verify that the analytical performance of UV-Vis spectrophotometers is suitable for the intended operational range of the analysis.

Title:  The Dissolution Procedure: Development and Validation  

Scope:  Addresses the development and validation of dissolution methods, with a focus on solid oral dosage forms. Many of the concepts presented may be applicable to other dosage forms and routes of administration.

Title:  Semisolid Drug Products—Performance Tests   

Scope:  Provides general information for performance testing of semisolid drug products, various types of equipment employed for such testing, and potential applications of the performance testing.